Tuberculosis Research Center, Chennai-AdvanTrial

This software application facilitates clinical trials that test the efficacy

of new drugs/treatments for TB-HIV. As a large amount of data is captured and

analyzed, TRC wanted to move from a paper-based data collection and analysis

system to a fully computerized one, which would enable them to manage larger

sample populations of patients and enhance the efficiency of the staff managing

these trials across multiple sites.

The capture of patients records began by their filling 73 CRFs (Case Report

Forms), which were processed through different phases of automated workflow,

namely an Assessment Phase, Intensive Phase, Monthly Phase, Continuation Phase

and DOTS/ Non-DOTS Phase. Additional supportive functions of the application are

Alerts, Reminders, Queries, and an internal Mail Box. This application automates

registration, enrolment, consultation, laboratory tests, patient case dockets

(electronic case history), task scheduling/lists, and all other features related

to clinical trial protocols, besides providing dashboards, reporting and data

export to SAS. The application uses .NET Framework 2.0, C#.NET and ASP.NET, with

SQL Server 2000 as the database.